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Old 06-28-2016, 04:19 AM   #1
Pipandor
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Join Date: Mar 2016
Posts: 3
Chest pain anyone?

Hello everyone,

I had my first Herceptin only infusion nearly three weeks ago, after 12 weekly taxol/herceptin infusions. I felt some strong chest pain a little left of the sternum during the first week after infusion and the pain has lingered, though less strong, ever since. I am worried it might happen again after this week's infusion.

My initial heart scan and the 3 month follow up showed that my left ventricular ejection fraction is holding steady at 65. A recent bone scan showed no mets.

I can't take ibuprofen because I am on daily injections of an anticoagulant (Fragmin), but I have taken Tylenol, which had no effect on the pain. I have had acid reflux in the past, and this doesn't feel like reflux.

I am new to the forum and hoping someone can share if they've experienced this. I would hate to stop taking Herceptin but concerned about heart damage.
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Invasive or Infiltrating Ductal Carcinoma (IDC) - January 2016
Left, 1cm, Stage IA, Grade 3, 0/3 nodes, ER-/PR-, HER2 +++
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Old 06-30-2016, 07:29 AM   #2
jra40
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Location: Pittsburgh, PA.
Posts: 199
Re: Chest pain anyone?

Hello! Did you talk to your oncologist about this? I know that when I was going through chemo/Herceptin, anything I felt that was out of the norm and was a concern, I told my doctor. She would always follow up with some type of test to make sure all was okay.

Good luck and pray it's nothing serious!
__________________
11/17/10 - Diagnosed with 4.5cm tumor in right breast, IDC, Stage 2, Nuclear grade 2, ER+ PR+ HER2+
12/13/10 - Lymph node biopsy - negative
12/28/10 - Started neo-adjuvant treatment along with clinical trial with 4 rounds of AC chemo every 3 weeks
3/15/11 - Began weekly Taxol/Herceptin infusions along with 750mg of Tykerb taken by mouth daily
6/28/11 - Finished last cycle of Taxol
7/27/11 - Breast MRI shows tumor has dissolved, remarkable reaction to chemo
8/31/11 - Lumpectomy, Sentinel Node biopsy. Node negative, clear margins, 7mm of cancer left over from chemo.
10/05/11 - Started radiation, 5 days a week for 7 weeks.
11/8/11 - Finished radiation
3/21/12 - Last Herceptin!
3/26/12 - Port removed!
Tamoxifen for 5 years
8/4/15 - Hysterectomy & bilateral salpingo-oophorectomy. Due to large fibroids. No cancer!
8/8/15 - Started Arimidex
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Old 06-30-2016, 12:18 PM   #3
Pipandor
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Re: Chest pain anyone?

Thank you JRA40. It's so nice to see that you are 5 years out and doing well. My oncologist is a little dismissive and I only see her every 3 weeks. Here in Canada, we can't always choose our doctors and when we see them.

The good news is that I requested that yesterday's infusion be administered over 60 rather than 30 minutes and so far, no chest pain. Fingers crossed that it will continue that way.
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Invasive or Infiltrating Ductal Carcinoma (IDC) - January 2016
Left, 1cm, Stage IA, Grade 3, 0/3 nodes, ER-/PR-, HER2 +++
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Old 07-01-2016, 10:00 AM   #4
#1son
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Re: Chest pain anyone?

Are you receiving infusions via peripheral vein (arm) or via an infusa-port (surgically implanted port)? Many ports use tubing that ends just above the heart. If you're experiencing pain related to infusion via such a device, you may want to mention this to the surgeon who installed it. Imaging may reveal any misplacement/migration of the tubing into contact with the heart/valve. This is very unlikely, but, again, it couldn't hurt to just mention it to the surgeon.
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Mom's stats:
2001: Hx H/O contralateral Right Breast Cancer: pT1bN0, ER/PR+, HER2 Neg, mastectomy
11/2015: Abnormal finding on mammogram
12/4/15: US-guided biopsy
12/10/15: Dx Left Breast Cancer, ER+/PR+, HER2 equivocal by IHC
12/15/15: HER2+ by FISH
12/21/15: Lumpectomy/axillary LN removal; 2 sentinel nodes=both Ca+
12/29/15: T1cN1M0, ER+/PR+/HER2+, Gr3, IDC & DCIS; 16 axillary nodes=all Ca-; Stage 2a; drain removed; f/u with Med Onc

1/14/16: little purple power port installed
1/20/16: Cycle 1, TCH (+ Neulasta on next day)
2/10/16: Cycle 2, TCH (+ Neulasta on next day)
3/2/16: Cycle 3, TCH (+ Neulasta on next day)
3/23/16: Cycle 4, TCH (+ Neulasta on next day)

4/13/16: Cycle 5, CH (stopped Taxotere due to increasing numbness in extremities) (+ Neulasta on next day)
5/4/16: Cycle 6, H (stopped Carboplatin due to severe, life-threatening anemia) (stopped Neulasta) Rec'd 2 units pRBCs. F-up blood draw in 1 wk
6/6/16: started 16 cycles of radiation (followed by 4 booster doses)

7/1/16: last booster dose today--no more radiation!
12/16: last Herceptin!
1/24/17: port removed!


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Old 07-05-2016, 09:02 AM   #5
jra40
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Location: Pittsburgh, PA.
Posts: 199
Re: Chest pain anyone?

#1Son - Good post and thinking, I did not think about the port causing the problem. I know my port was inserted in my neck and threaded through the chest. Had a hard time sleeping on one side and certainly noticed some difference in my heart rhythms!
__________________
11/17/10 - Diagnosed with 4.5cm tumor in right breast, IDC, Stage 2, Nuclear grade 2, ER+ PR+ HER2+
12/13/10 - Lymph node biopsy - negative
12/28/10 - Started neo-adjuvant treatment along with clinical trial with 4 rounds of AC chemo every 3 weeks
3/15/11 - Began weekly Taxol/Herceptin infusions along with 750mg of Tykerb taken by mouth daily
6/28/11 - Finished last cycle of Taxol
7/27/11 - Breast MRI shows tumor has dissolved, remarkable reaction to chemo
8/31/11 - Lumpectomy, Sentinel Node biopsy. Node negative, clear margins, 7mm of cancer left over from chemo.
10/05/11 - Started radiation, 5 days a week for 7 weeks.
11/8/11 - Finished radiation
3/21/12 - Last Herceptin!
3/26/12 - Port removed!
Tamoxifen for 5 years
8/4/15 - Hysterectomy & bilateral salpingo-oophorectomy. Due to large fibroids. No cancer!
8/8/15 - Started Arimidex
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Old 07-26-2016, 08:09 AM   #6
Colleen
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Join Date: Jun 2014
Location: Monarch Beach, CA
Posts: 74
Re: Chest pain anyone?

@Pipandor I frequently had chest discomfort during my infusions when I had my port but it did not linger after the infusion was finished. I demanded my port be removed even though I am a stage 4 cancer thriver. It was uncomfortable and extremely inefficient, besides I have great veins. I would bring this up to the nurses and doctor every time it happens, squeaky wheel gets the oil. At times I have felt my oncologist to be dismissive when I brought up things that seemed "off" to me. Even though these doctors have a lot of experience they have not personally gone through what we have been through so they really don't have any "firsthand" experience.
__________________
*October 2013 mammogram suspicious lump right breast
*Oct. 2013 Breast MRI reveals 2.5 cm tumor right breast 6-7 nodes positive
*Nov 2, 2013 PET/CT tumor right breast, 6-7 nodes include right axilla and one above clavicle, 3.5 cm lesion on dome of liver
*Nov 4, 2013 meet oncologist: schedule port placement
*Nov 5, 2013 baseline echo 65%
*Nov 13, 2013 start THP six cycles every 21 days
*Nov 20, 2013 blood counts now coming back quickly start neulasta following next treatment, no pain and it worked!
*Jan 19, 2014 syncope, ambulance ride to hospital, cracked a tooth and chipped three, six stitches in chin, CT scan shows brain is ok but am required to follow up with neurologist.
*Jan 28, 2014 PET/CT shows great response to THP
*Jan 28, 2013 echo, all is good 60-65%
*Feb 2014 brain MRI, no missing parts and no extra parts, all clear
*Feb 27, 2014 last treatment with taxotere
*Apr 22, 2014 PET/CT shows complete pathological response to THP amen!
*Apr 22, 2013 echo 60%
*continue vitamin H and P every 21 days until...eternity?
*May 2014 emotional melt down, demand port be removed.
*May 22 2014, biopsy of original tumor rt. breast, no cancer cells in 8 tissue samples, amen
*June 2, 2014 Port removed, happy dance! Just couldn't tolerate the port any longer; it never worked properly and was extremely uncomfortable
*July 24, 2014 echo 60%
*August 28, 2014 PET/CT all clear NED
*Oct 29, 2014 echo 65%
*Feb 4, 2015 PET/CT NED!!!
*Feb 4, 2015 Echo 65-70%
*May 19, 2015 mammogram all clear
*May 19, 2015 Brain MRI all clear!
*August 18, 2015 PET/CT NED!!! amen!
*March 8, 2016 CT w/contrast NED
*March 10, 2016 Echo normal
*June 2016 Echo normal
*September 7, 2016 CT scan w/contrast NED
*September 8, 2016 Echo normal
* stille receiving infusions every 21 days of Perjeta and Herceptin with no end in sight......

"Better pass boldly into that other world, in the full glory of some passion, than fade and wither dismally with age."
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